Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026144 | 0.87 | HRH3 (0.46) | HRH3HTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL9026137 | 0.86 | HRH3 (0.43) | HRH3HTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL9026529 | 0.82 | HRH3 (0.59) | HRH3HTR2CCHRNA7HRH4BCHE | |
| SCHEMBL9027181 | 0.81 | KDM4E (0.43) | HRH3KMT2AMAPTCHRNA7HRH4 | |
| SCHEMBL9027007 | 0.77 | HTR2C (0.48) | HTR2CHTR2BCHRM2CHRM4CHRM1 | |
| SCHEMBL9223734 | 0.73 | HRH3 (0.44) | HRH3HTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL9027042 | 0.72 | HRH3 (0.56) | HRH3HTR2CKMT2ACHRNA7HRH4 | |
| SCHEMBL9027112 | 0.69 | IDO1 (0.38) | HRH3ALDH1A1KDM4EHPGD | |
| SCHEMBL9027395 | 0.69 | MTNR1A (0.39) | MEN1KMT2ACHRNA7HPGDTDP1 | |
| SCHEMBL9026022 | 0.69 | ACKR3 (0.39) | HTR2CSMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537532-B1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5326879-A | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0537532-A1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |