Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733153 | 0.86 | CCR1 (0.52) | CCR1CCR8GRM5TGFBR1MAPK14 | |
| SCHEMBL15470589 | 0.85 | CCR1 (0.60) | CCR1CCR8GRM5TGFBR1MAPK14 | |
| SCHEMBL1555066 | 0.81 | KDM4E (0.43) | CCR1CCR8GRM5TGFBR1MAPK14 | |
| SCHEMBL29929279 | 0.81 | KDM4E (0.43) | CCR1CCR8GRM5TGFBR1MAPK14 | |
| SCHEMBL14732986 | 0.79 | TGFBR1 (0.43) | CCR1CCR8GRM5TGFBR1METAP2 | |
| SCHEMBL8854902 | 0.77 | MEN1 (0.55) | CCR1CCR8GRM5TGFBR1CYP2A6 | |
| SCHEMBL3419835 | 0.77 | CCR1 (0.73) | CCR1CCR8GRM5TGFBR1MAPK14 | |
| SCHEMBL7964553 | 0.76 | KDM4E (0.59) | CCR1CCR8GRM5KDM4EALDH1A1 | |
| SCHEMBL21977980 | 0.75 | IDH1 (0.51) | TGFBR1 | |
| SCHEMBL10368628 | 0.73 | GRM5 (0.39) | CCR1CCR8GRM5TGFBR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459662-B1 | Fungicidal compounds | ZENECA LTD (GB) | 1996-08-21 | — | — | EP | disclosed |
| EP-0557291-B1 | PYRIDIL-PYRIMIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | ZENECA LTD (GB) | 1996-08-14 | — | — | EP | disclosed |
| EP-0557291-A1 | PYRIDIL-PYRIMIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS. | ICI PLC (GB) | 1993-09-01 | — | — | EP | disclosed |
| US-5208239-A | Plant fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-04 | — | — | US | disclosed |
| US-5185339-A | FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-09 | — | — | US | disclosed |
| WO-1992008714-A1 | PYRIDIL-PYRIMIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-29 | — | — | WO | disclosed |
| CN-1058019-A | FUNGICIDAL COMPOUNDS | ICI PLC (GB) | 1992-01-22 | — | — | CN | disclosed |
| EP-0459662-A1 | Fungicidal compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |
| US-4927827-A | Pyridinylpyrimidine derivatives, method for production thereof and a fungicide containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-22 | — | — | US | disclosed |