Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MGAM | O43451 | 2/20 | 0.53 |
| ▸ | SI | P14410 | 2/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757460 | 0.80 | HTR2C (0.50) | HTR2CHTR2AHTR2BADRB2GAA | |
| SCHEMBL31295110 | 0.79 | HTR2A (0.53) | HTR2CHTR2AHTR2BADRB2GAA | |
| SCHEMBL31295157 | 0.76 | IDO1 (0.49) | HTR2CHTR2AHTR2BADRB2GAA | |
| SCHEMBL734917 | 0.76 | HTR2C (0.79) | HTR2CHTR2AHTR2BADRB2KDM4E | |
| SCHEMBL25324193 | 0.74 | GAA (0.54) | HTR2CHTR2AHTR2BADRB2GAA | |
| SCHEMBL27975863 | 0.74 | HTR2C (0.58) | HTR2CHTR2AHTR2BADRB2GAA | |
| SCHEMBL13255020 | 0.73 | HTR2C (0.41) | HTR2CHTR2AHTR2BADRB2GAA | |
| SCHEMBL807343 | 0.73 | HTR2C (0.74) | HTR2CHTR2AHTR2BADRB2KDM4E | |
| SCHEMBL28594057 | 0.73 | HTR2C (0.74) | HTR2CHTR2AHTR2BADRB2KDM4E | |
| SCHEMBL19180060 | 0.73 | HTR2C (0.51) | HTR2CHTR2AHTR2BADRB2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558950-B1 | 3-aryl-glycidic ester derivatives and process for their preparation | PHARMACIA SPA (IT) | 1996-12-04 | — | — | EP | disclosed |
| US-5436235-A | 3-aryl-glycidic ester derivatives | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-07-25 | — | — | US | disclosed |
| EP-0558950-A1 | 3-aryl-glycidic ester derivatives and process for their preparation | PHARMACIA S.p.A. (IT) | 1993-09-08 | — | — | EP | disclosed |