Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.74 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.74 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910862 | 0.98 | HTR2C (0.72) | HTR2CADRB2ADRA1DKDM4EATM | |
| SCHEMBL28594057 | 0.96 | HTR2C (0.74) | HTR2CADRB2ADRA1DKDM4EATM | |
| SCHEMBL734917 | 0.92 | HTR2C (0.79) | HTR2CADRB2ADRA1DKDM4EATM | |
| SCHEMBL373923 | 0.85 | HTR2C (1.00) | HTR2CADRB2ADRA1DKDM4EATM | |
| SCHEMBL29502102 | 0.85 | HTR2C (1.00) | HTR2CADRB2ADRA1DKDM4EATM | |
| SCHEMBL6637446 | 0.85 | HTR2C (0.70) | HTR2CADRB2ADRA1DKDM4EATM | |
| SCHEMBL1601125 | 0.84 | HTR2C (0.68) | HTR2CADRB2ADRA1DKDM4EATM | |
| Hydrochloric Acid SCHEMBL31285949 | 0.84 | HTR2C (1.00) | HTR2CADRB2ADRA1DKDM4EATM | |
| Methane SCHEMBL10788775 | 0.84 | HTR2C (0.97) | HTR2CADRB2ADRA1DKDM4EATM | |
| SCHEMBL27779740 | 0.84 | HTR2C (0.68) | HTR2CADRB2ADRA1DKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101830-B | A kind of 3- replaces the preparation method of Oxoindole and derivative | 中国科学院成都生物研究所 | 2019-08-23 | — | — | CN | disclosed |
| US-9271971-B2 | Pyrido[3,4-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150352087-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. | 2015-12-10 | — | — | US | disclosed |
| US-9085580-B2 | Pyrido[3,4-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-9079904-B2 | Pyrido[3,4-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-07-14 | — | — | US | disclosed |
| US-20130190308-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| WO-2012036315-A1 | METHOD OF FORMING PATTERN | FUJIFILM CORPORATION (JP) | 2012-03-22 | — | — | WO | disclosed |
| US-20110237582-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. | 2011-09-29 | — | — | US | disclosed |
| CN-100569863-C | Indoline-like photosensitive dyestuff and uses thereof | UNIV EAST CHINA SCIENCE & TECH (CN) | 2009-12-16 | — | — | CN | disclosed |
| CN-101165103-A | Indoline-like photosensitive dyestuff and application thereof | EAST CHINA UNIVERSITY OF TECHN (CN) | 2008-04-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190308-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | HTR3B, HTR4, HTR2C | HTR2C 3/4885ADRB2 210/4885ADRA1D 275/4885 |
| US-20150352087-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | HTR3B, HTR4, HTR2C | HTR2C 3/4885ADRB2 210/4885ADRA1D 275/4885 |
| US-20110237582-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | HTR3B, HTR4, HTR2C | HTR2C 3/4885ADRB2 210/4885ADRA1D 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.