Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.66 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775955 | 0.83 | HRH3 (0.78) | HRH3CHRNA7HRH4KDM4EHSD17B10 | |
| SCHEMBL10508496 | 0.82 | HRH3 (0.97) | HRH3CHRNA7HRH4KDM4EHSD17B10 | |
| SCHEMBL31061131 | 0.80 | HRH3 (1.00) | HRH3CHRNA7HRH4KDM4EHSD17B10 | |
| SCHEMBL8332622 | 0.78 | HRH3 (0.65) | HRH3CHRNA7HRH4CHRM2CHRM1 | |
| SCHEMBL3990045 | 0.77 | HRH3 (0.63) | HRH3CHRNA7HRH4CHRM2CHRM1 | |
| SCHEMBL9027107 | 0.76 | HRH3 (0.66) | HRH3CHRNA7HRH4KDM4EHSD17B10 | |
| SCHEMBL9027275 | 0.75 | HRH3 (0.67) | HRH3CHRNA7HRH4KDM4EHSD17B10 | |
| SCHEMBL9026162 | 0.74 | HRH3 (0.63) | HRH3CHRNA7HRH4KDM4EHSD17B10 | |
| SCHEMBL9223267 | 0.74 | HRH3 (0.66) | HRH3CHRNA7HRH4KDM4EHSD17B10 | |
| SCHEMBL9027269 | 0.74 | HRH3 (0.65) | HRH3CHRNA7HRH4KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537532-B1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5380723-A | Antiulcer | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5326879-A | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0537532-A1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |