Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952366 | 1.00 | MAPK1 (0.45) | MAPK1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL8803669 | 0.93 | MAPK1 (0.51) | MAPK1ALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL8952280 | 0.89 | MAPK1 (0.48) | MAPK1ALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL8952260 | 0.86 | MAPK1 (0.54) | MAPK1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL7993503 | 0.86 | MAPK1 (0.45) | MAPK1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL6257143 | 0.86 | MAPK1 (0.45) | MAPK1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL8952196 | 0.85 | ALDH1A1 (0.47) | MAPK1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL8952343 | 0.85 | ALDH1A1 (0.47) | MAPK1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL9118286 | 0.85 | ALDH1A1 (0.47) | MAPK1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL8952264 | 0.85 | ALDH1A1 (0.47) | MAPK1ALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662834-A4 | NOVEL EPOXIDE-CONTAINING COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0662834-A1 | NOVEL EPOXIDE-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994006431-A1 | NOVEL EPOXIDE-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-03-31 | — | — | WO | disclosed |