Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7180089 | 1.00 | SMPD1 (0.48) | SMPD1LPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL9711433 | 1.00 | SMPD1 (0.48) | SMPD1LPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL9026274 | 1.00 | SMPD1 (0.48) | SMPD1LPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL7185870 | 1.00 | SMPD1 (0.48) | SMPD1LPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL7182172 | 0.92 | SMPD1 (0.56) | SMPD1LPAR3LPAR1LPAR2PTPN1 | |
| SCHEMBL7192780 | 0.92 | SMPD1 (0.56) | SMPD1LPAR3LPAR1LPAR2PTPN1 | |
| SCHEMBL7183671 | 0.92 | SMPD1 (0.56) | SMPD1LPAR3LPAR1LPAR2PTPN1 | |
| SCHEMBL9026174 | 0.91 | SMPD1 (0.49) | SMPD1LPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL7185533 | 0.91 | SMPD1 (0.49) | SMPD1LPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL9130340 | 0.91 | SMPD1 (0.49) | SMPD1LPAR3LPAR1LPAR2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5097878-A | — | — | None | — | — | JP | disclosed |
| EP-0507337-B1 | Novel erucyl, brassidyl and nervonyl derivatives | MAX PLANCK GESELLSCHAFT (DE) | 1996-10-23 | — | — | EP | disclosed |
| US-5436234-A | Treatment of protozoal and fungal diseases, autoimmune diseases and bone marrow damage | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG (DE) | 1995-07-25 | — | — | US | disclosed |
| JP-H0597878-A | ERUCYL-, BRASSIDYL-, AND NERVONYL DERIVATIVES, PRODUCTION OF THE SAME, MEDICINES CONTAINING THE SAME TO TREAT TUMORS, DISEASES INCURRED BY PROTOZOA AND FUNGAS, AUTOIMMUNE DISEASES AND BONE MARROW DISORDERS, AND PREPARATION OF THE SAME MEDICINES | MAX PLANCK GES FOERDERUNG WISSENSCHAFT EV | 1993-04-20 | — | — | JP | disclosed |
| EP-0507337-A2 | Novel erucyl, brassidyl and nervonyl derivatives | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1992-10-07 | — | — | EP | disclosed |