Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027302 | 0.90 | CYP19A1 (0.33) | CYP19A1MMP2ANPEP | |
| SCHEMBL9027186 | 0.88 | CYP19A1 (0.33) | CYP19A1HSD17B10 | |
| SCHEMBL9026908 | 0.85 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL9027934 | 0.80 | CYP19A1 (0.33) | CYP19A1MMP2ANPEP | |
| SCHEMBL9025956 | 0.80 | CYP19A1 (0.33) | CYP19A1MMP2ANPEP | |
| SCHEMBL9027198 | 0.78 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL9369640 | 0.77 | CYP19A1 (0.32) | CYP19A1MMP2ANPEP | |
| SCHEMBL9026391 | 0.76 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL9220068 | 0.76 | SIGMAR1 (0.33) | CYP19A1MMP2ANPEP | |
| SCHEMBL8833776 | 0.76 | SIGMAR1 (0.33) | CYP19A1MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |