Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027869 | 0.89 | SCN10A (0.47) | ALDH1A1TSHRSMPD1MEN1KMT2A | |
| SCHEMBL9027887 | 0.74 | MAPT (0.40) | TSHRSMPD1NPC1RAB9AMEN1 | |
| SCHEMBL9027944 | 0.71 | NPC1 (0.39) | ALDH1A1SMPD1NPC1RAB9AMEN1 | |
| SCHEMBL9027817 | 0.71 | MAPT (0.43) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8602667 | 0.70 | MAPT (0.36) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9265857 | 0.70 | PTGS1 (0.38) | ALDH1A1TSHRHSD17B10NPC1RAB9A | |
| SCHEMBL9028921 | 0.69 | TAS2R14 (0.39) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL9029108 | 0.69 | TAS2R14 (0.39) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL9027553 | 0.69 | PTGDR2 (0.34) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL7174521 | 0.69 | PTGDR2 (0.38) | ALDH1A1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544587-B1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-05-29 | — | — | EP | claimed |