Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9028181 | 0.99 | DRD2 (0.48) | DRD2 | |
| SCHEMBL9028135 | 0.89 | DRD2 (0.50) | DRD2 | |
| Hydrochloric Acid SCHEMBL9027301 | 0.89 | DRD2 (0.46) | DRD2 | |
| Hydrochloric Acid SCHEMBL9027010 | 0.88 | DRD2 (0.47) | DRD2 | |
| Hydrochloric Acid SCHEMBL9028286 | 0.85 | DRD2 (0.61) | DRD2 | |
| SCHEMBL9026064 | 0.84 | MAPK1 (0.48) | DRD2 | |
| Hydrochloric Acid SCHEMBL9027012 | 0.83 | MAPK1 (0.47) | DRD2 | |
| Hydrochloric Acid SCHEMBL9026528 | 0.81 | — | — | |
| SCHEMBL8828736 | 0.79 | TSHR (0.41) | — | |
| Hydrochloric Acid SCHEMBL8828706 | 0.78 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711757-A1 | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists | F. Hoffmann-La Roche AG (CH) | 1996-05-15 | — | — | EP | disclosed |