Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 4/20 | 0.42 |
| ▸ | TACR1 | P25103 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027505 | 1.00 | TACR2 (0.42) | TACR2TACR1MEN1KMT2ATACR3 | |
| SCHEMBL9029048 | 0.97 | TACR2 (0.42) | TACR2TACR1TACR3CCR5 | |
| SCHEMBL9026960 | 0.97 | TACR2 (0.42) | TACR2TACR1TACR3CCR5 | |
| SCHEMBL8882055 | 0.94 | TACR1 (0.46) | TACR2TACR1 | |
| SCHEMBL8883694 | 0.94 | TACR1 (0.46) | TACR2TACR1 | |
| SCHEMBL9028344 | 0.91 | MEN1 (0.40) | TACR1MEN1KMT2A | |
| SCHEMBL9028382 | 0.91 | MEN1 (0.40) | TACR1MEN1KMT2A | |
| SCHEMBL9028480 | 0.91 | MEN1 (0.40) | TACR1MEN1KMT2A | |
| SCHEMBL9027486 | 0.91 | MEN1 (0.41) | TACR1MEN1KMT2A | |
| SCHEMBL9027567 | 0.90 | MEN1 (0.43) | TACR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563133-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0714891-A1 | Heterocyclic tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |