⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147092 | 0.82 | — | — | |
| SCHEMBL5992994 | 0.75 | — | — | |
| SCHEMBL3261673 | 0.70 | TDP1 (0.38) | — | |
| SCHEMBL11819885 | 0.70 | — | — | |
| SCHEMBL2619 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL18838097 | 0.67 | — | — | |
| SCHEMBL2154678 | 0.67 | TDP1 (0.35) | — | |
| SCHEMBL4883615 | 0.67 | — | — | |
| SCHEMBL483531 | 0.67 | — | — | |
| SCHEMBL17707871 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621535-A1 | THIAZOLIDINE LINKER FOR THE CONJUGATION OF DRUGS TO ANTIBODIES | Philogen S.p.A. (IT) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041451-A1 | THIAZOLIDINE LINKER FOR THE CONJUGATION OF DRUGS TO ANTIBODIES | PHILOGEN S.P.A. (IT) | 2012-04-05 | — | — | WO | disclosed |