Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 7/20 | 0.46 |
| ▸ | TACR1 | P25103 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TACR3 | P29371 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882906 | 0.96 | TACR2 (0.49) | KMT2AMEN1GAAHTTTACR2 | |
| SCHEMBL8882895 | 0.96 | TACR2 (0.49) | KMT2AMEN1GAAHTTTACR2 | |
| SCHEMBL9027244 | 0.90 | KMT2A (0.47) | KMT2AMEN1GAAHTTTACR2 | |
| SCHEMBL9028177 | 0.88 | TACR1 (0.56) | TACR2TACR1CCR5 | |
| SCHEMBL8883870 | 0.86 | KMT2A (0.46) | KMT2AMEN1GAAHTTTACR2 | |
| SCHEMBL8883877 | 0.86 | KMT2A (0.46) | KMT2AMEN1GAAHTTTACR2 | |
| SCHEMBL8883323 | 0.84 | TACR1 (0.60) | TACR2TACR1CCR5 | |
| SCHEMBL8883332 | 0.84 | TACR1 (0.60) | TACR2TACR1CCR5 | |
| SCHEMBL9028345 | 0.83 | KDM4E (0.42) | KMT2AMEN1GAAHTTTACR2 | |
| SCHEMBL9027155 | 0.81 | MEN1 (0.52) | KMT2AMEN1GAAHTTTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563133-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0714891-A1 | Heterocyclic tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |