Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TACR2 | P21452 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | TACR3 | P29371 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884481 | 0.94 | MEN1 (0.47) | MEN1KMT2AGAAHTTTACR2 | |
| SCHEMBL9028736 | 0.89 | MEN1 (0.52) | MEN1KMT2AGAAHTTTACR2 | |
| SCHEMBL8884091 | 0.82 | MEN1 (0.47) | MEN1KMT2AGAAHTTTACR2 | |
| SCHEMBL8884449 | 0.82 | TACR2 (0.55) | MEN1KMT2ATACR2TACR1 | |
| SCHEMBL9028341 | 0.81 | KMT2A (0.47) | MEN1KMT2AGAAHTTTACR2 | |
| SCHEMBL9027159 | 0.78 | KDM4E (0.39) | MEN1KMT2AGAAHTTPKM | |
| SCHEMBL8953928 | 0.78 | TACR1 (0.59) | TACR2TACR1TACR3 | |
| SCHEMBL8882906 | 0.77 | TACR2 (0.49) | MEN1KMT2AGAAHTTTACR2 | |
| SCHEMBL8882895 | 0.77 | TACR2 (0.49) | MEN1KMT2AGAAHTTTACR2 | |
| SCHEMBL6951866 | 0.76 | TACR2 (0.62) | TACR2TACR1TACR3CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563133-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0714891-A1 | Heterocyclic tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |