Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 2/20 | 0.45 |
| ▸ | ALPG | P10696 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570175 | 0.86 | FGFR1 (0.55) | FGFR1F10KMT2AF2HPGD | |
| SCHEMBL9598051 | 0.86 | FGFR1 (0.55) | FGFR1F10KMT2AF2HPGD | |
| SCHEMBL22160858 | 0.85 | HPGD (0.56) | FGFR1F10KMT2AHPGDNPC1 | |
| SCHEMBL4313511 | 0.84 | F10 (0.61) | FGFR1F10F2MAPTHSD17B10 | |
| SCHEMBL23986927 | 0.84 | FGFR1 (0.52) | FGFR1F10KMT2AF2HPGD | |
| SCHEMBL29868198 | 0.83 | HPGD (0.67) | FGFR1F10KMT2AHPGDNPC1 | |
| SCHEMBL22134963 | 0.82 | HPGD (0.62) | FGFR1F10KMT2AHPGDNPC1 | |
| SCHEMBL16318608 | 0.79 | FGFR1 (0.60) | FGFR1F10KMT2AHPGDJAK2 | |
| SCHEMBL1299105 | 0.79 | FGFR1 (0.60) | FGFR1KMT2AHPGDJAK2JAK1 | |
| SCHEMBL30980884 | 0.79 | L3MBTL1 (0.65) | FGFR1F10KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720603-A1 | BIS(AMIDINOBENZIMIDAZOLYL)ALKANES AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-07-10 | — | — | EP | disclosed |