SCHEMBL9028497

SCHEMBL9028497

C=CCCCCCCCC1CCC(=O)NC1=O

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 16/20 0.42
DDB1 Q16531 2/20 0.42
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952307 0.98 CRBN (0.43) CRBNDDB1POLBKMT2A
SCHEMBL20359431 0.94 CRBN (0.44) CRBNDDB1POLBKMT2A
SCHEMBL20206912 0.87 CRBN (0.46) CRBNDDB1
SCHEMBL8952198 0.81 POLB (0.41) CRBNDDB1POLBKMT2A
SCHEMBL18379287 0.79 POLB (0.54) CRBNDDB1POLBKMT2A
SCHEMBL732924 0.79 POLB (0.54) CRBNDDB1POLBKMT2A
SCHEMBL732367 0.79 POLB (0.54) CRBNDDB1POLBKMT2A
SCHEMBL3042782 0.78 FAAH (0.44) CRBNDDB1
Acrylic Acid SCHEMBL31065402 0.77 POLB (0.44) CRBNDDB1POLBKMT2A
SCHEMBL723934 0.77 POLB (0.55) CRBNDDB1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0662834-A4 NOVEL EPOXIDE-CONTAINING COMPOUNDS. CELL THERAPEUTICS INC (US) 1996-04-17 EP disclosed
EP-0662834-A1 NOVEL EPOXIDE-CONTAINING COMPOUNDS CELL THERAPEUTICS, INC. (US) 1995-07-19 EP disclosed
WO-1994006431-A1 NOVEL EPOXIDE-CONTAINING COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-03-31 WO disclosed