Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081055 | 0.82 | SLC6A3 (0.41) | SLC6A3OPRK1ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL6947257 | 0.79 | SLC6A3 (0.37) | SLC6A3OPRK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7956480 | 0.77 | MEN1 (0.39) | SLC6A3OPRK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8564397 | 0.76 | SLC6A3 (0.38) | SLC6A3OPRK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6952332 | 0.74 | SLC6A3 (0.36) | SLC6A3OPRK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8485274 | 0.73 | MEN1 (0.36) | SLC6A3OPRK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8484373 | 0.73 | MEN1 (0.38) | SLC6A3OPRK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6543753 | 0.73 | MEN1 (0.38) | SLC6A3OPRK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8352404 | 0.73 | SLC6A3 (0.44) | SLC6A3OPRK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7956476 | 0.72 | MEN1 (0.41) | SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714891-A1 | Heterocyclic tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |