Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028555 | 0.80 | TSHR (0.44) | TSHREPHX2POLB | |
| SCHEMBL10035281 | 0.77 | SLC6A2 (0.51) | SLC6A2SLC6A3SLC6A4EPHX2 | |
| SCHEMBL8629644 | 0.75 | TSHR (0.50) | TSHRSLC6A2SLC6A3SLC6A4PTGDR | |
| SCHEMBL8629643 | 0.75 | TSHR (0.50) | TSHRSLC6A2SLC6A3SLC6A4PTGDR | |
| SCHEMBL14446350 | 0.72 | TSHR (0.54) | TSHRPOLBHPGD | |
| SCHEMBL13765234 | 0.72 | TSHR (0.46) | TSHRPTGDRPOLBHPGD | |
| SCHEMBL8629646 | 0.71 | TSHR (0.50) | TSHRPOLBHPGD | |
| SCHEMBL2484638 | 0.71 | ESR2 (0.53) | TSHRPTGDRPOLBHPGD | |
| SCHEMBL2484641 | 0.71 | ESR2 (0.53) | TSHRPTGDRPOLBHPGD | |
| SCHEMBL7701922 | 0.70 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4EPHX2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |