Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 8/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24449591 | 0.89 | FFAR4 (0.42) | ACACBFFAR4EGFRALDH1A1MAPT | |
| SCHEMBL9028562 | 0.80 | TSHR (0.41) | TSHRPOLBEPHX2 | |
| SCHEMBL8840546 | 0.80 | CYP2D6 (0.47) | TSHRPOLBFFAR4ALDH1A1MAPT | |
| SCHEMBL8840553 | 0.80 | CYP2D6 (0.47) | TSHRPOLBFFAR4ALDH1A1MAPT | |
| SCHEMBL470126 | 0.78 | ACHE (0.46) | POLBEGFRALDH1A1KMT2AMAPT | |
| SCHEMBL15748399 | 0.77 | HRH3 (0.40) | ACACBEGFREPHX2HRH3 | |
| SCHEMBL14446350 | 0.77 | TSHR (0.54) | TSHRPOLBALDH1A1KMT2AKDM4E | |
| SCHEMBL8629644 | 0.76 | TSHR (0.50) | TSHRPOLBALDH1A1KMT2ADHODH | |
| SCHEMBL2484638 | 0.76 | ESR2 (0.53) | TSHRPOLBALDH1A1KMT2AKDM4E | |
| SCHEMBL2484641 | 0.76 | ESR2 (0.53) | TSHRPOLBALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |