Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082426 | 1.00 | PDE10A (0.44) | PDE10A | |
| SCHEMBL896975 | 1.00 | PDE10A (0.44) | PDE10A | |
| SCHEMBL10082424 | 0.85 | PDE10A (0.48) | PDE10A | |
| SCHEMBL10086338 | 0.81 | PDE10A (0.45) | PDE10A | |
| SCHEMBL901926 | 0.80 | PDE10A (0.49) | PDE10A | |
| SCHEMBL14977342 | 0.74 | PDE10A (0.44) | PDE10A | |
| SCHEMBL17799051 | 0.74 | PDE10A (0.44) | PDE10A | |
| SCHEMBL901337 | 0.74 | PDE10A (0.44) | PDE10A | |
| SCHEMBL902793 | 0.72 | ALDH1A1 (0.43) | PDE10A | |
| SCHEMBL10086282 | 0.71 | PDE10A (0.40) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044561-A2 | 2-ALKOXY PYRIMIDINE PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |