Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | EIF4E | P06730 | 17/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027587 | 0.85 | PRKD3 (0.47) | MAPTEIF4EALDH1A1KDM4EMEN1 | |
| SCHEMBL9026772 | 0.83 | MAPT (0.46) | MAPTEIF4EKDM4EMEN1NPC1 | |
| SCHEMBL9566872 | 0.78 | EIF4E (0.44) | MAPTEIF4E | |
| SCHEMBL9566874 | 0.78 | EIF4E (0.44) | MAPTEIF4E | |
| SCHEMBL9401160 | 0.75 | PRKD3 (0.44) | MAPTEIF4EALDH1A1KDM4EMEN1 | |
| SCHEMBL9028613 | 0.74 | EIF4E (0.43) | MAPTEIF4EALDH1A1KDM4EMEN1 | |
| SCHEMBL9028732 | 0.73 | EIF4E (0.44) | MAPTEIF4EKDM4EMEN1NPC1 | |
| SCHEMBL9027009 | 0.72 | MAPT (0.45) | MAPTALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL25413652 | 0.70 | KDM4E (0.62) | MAPTEIF4EALDH1A1KDM4EMEN1 | |
| SCHEMBL9028452 | 0.69 | TRPA1 (0.34) | MAPTMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544587-B1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-05-29 | — | — | EP | disclosed |