Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696222 | 0.82 | CCNB2 (0.42) | TLR7TLR9SLC6A4 | |
| SCHEMBL9027913 | 0.82 | CCNB2 (0.42) | TLR7TLR9SLC6A4 | |
| SCHEMBL9026910 | 0.79 | CCNB2 (0.40) | TLR7TLR9MAPTSLC6A4 | |
| SCHEMBL8791452 | 0.78 | CCNB2 (0.48) | MAPT | |
| SCHEMBL8789465 | 0.76 | CCNB2 (0.42) | — | |
| SCHEMBL8789634 | 0.76 | CCNB2 (0.47) | — | |
| SCHEMBL9028683 | 0.76 | CCNB2 (0.40) | TLR7TLR8TLR9 | |
| SCHEMBL9029036 | 0.74 | TLR9 (0.41) | TLR7TLR8TLR9 | |
| SCHEMBL8790751 | 0.73 | CCNB2 (0.44) | MAPT | |
| SCHEMBL9029025 | 0.73 | FNTA (0.38) | TLR7TLR8TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736008-A1 | INDOLE DERIVATIVES AS ANTI-ESTROGENS | KARO BIO AB (SE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017383-A1 | INDOLE DERIVATIVES AS ANTI-ESTROGENS | KARO BIO AB (SE) | 1995-06-29 | — | — | WO | disclosed |