Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029025 | 0.84 | FNTA (0.38) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL7696222 | 0.80 | CCNB2 (0.42) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL9027913 | 0.80 | CCNB2 (0.42) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8791452 | 0.79 | CCNB2 (0.48) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8789465 | 0.78 | CCNB2 (0.42) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8789634 | 0.78 | CCNB2 (0.47) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL9026910 | 0.77 | CCNB2 (0.40) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL9029036 | 0.76 | TLR9 (0.41) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8790583 | 0.76 | CCNB2 (0.41) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL9028624 | 0.76 | TLR7 (0.42) | TLR9TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736008-A1 | INDOLE DERIVATIVES AS ANTI-ESTROGENS | KARO BIO AB (SE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017383-A1 | INDOLE DERIVATIVES AS ANTI-ESTROGENS | KARO BIO AB (SE) | 1995-06-29 | — | — | WO | disclosed |