Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.54 |
| ▸ | FPR2 | P25090 | 3/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.42 |
| ▸ | F9 | P00740 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425930 | 1.00 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1F9 | |
| SCHEMBL7420241 | 0.88 | ITGB3 (0.63) | ITGB3ITGA2BFPR2FPR1F9 | |
| Acetic Acid SCHEMBL9095758 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BFPR2FPR1F9 | |
| SCHEMBL7418392 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7418373 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7418509 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BF9 | |
| SCHEMBL7418384 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8115266 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BF9 | |
| SCHEMBL7417370 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BF9 | |
| Trifluoroacetic Acid SCHEMBL9028999 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BFPR2FPR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |