Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.57 |
| ▸ | FPR2 | P25090 | 3/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425949 | 1.00 | ITGB3 (0.57) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7420246 | 0.87 | ITGB3 (0.73) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL27350762 | 0.87 | ITGB3 (0.73) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7413110 | 0.83 | ITGB3 (0.75) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7075515 | 0.83 | ITGB3 (0.75) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7417376 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL7417379 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2B | |
| Acetic Acid SCHEMBL7418342 | 0.80 | ITGB3 (0.75) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7419100 | 0.79 | ITGB3 (0.42) | ITGB3ITGA2B | |
| SCHEMBL7419097 | 0.79 | ITGB3 (0.42) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | disclosed |