Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401109 | 0.88 | ALDH1A1 (0.39) | MAOBALDH1A1KDM4ECNR2RXFP1 | |
| SCHEMBL9401168 | 0.81 | GAA (0.44) | MAOBALDH1A1KDM4ELMNACES2 | |
| SCHEMBL9029110 | 0.80 | KMT2A (0.40) | MAOBALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL9028355 | 0.78 | MAPT (0.41) | MAOBLMNAMAPTMEN1NPC1 | |
| SCHEMBL9028837 | 0.71 | CNR2 (0.40) | MAOBALDH1A1KDM4ECNR2RXFP1 | |
| SCHEMBL28374551 | 0.70 | MAPT (0.58) | MAOBALDH1A1KDM4ERXFP1MAPT | |
| SCHEMBL28374548 | 0.70 | MAPT (0.58) | MAOBALDH1A1KDM4ERXFP1MAPT | |
| SCHEMBL9027944 | 0.70 | NPC1 (0.39) | ALDH1A1LMNAMAPTHPGDMEN1 | |
| SCHEMBL9120058 | 0.70 | AKR1C3 (0.43) | ALDH1A1MEN1KMT2AAKR1C3 | |
| SCHEMBL7824610 | 0.70 | PDK2 (0.54) | CNR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544587-B1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-05-29 | — | — | EP | disclosed |
| EP-0544587-A1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-06-02 | — | — | EP | disclosed |