Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781286 | 0.90 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL5018017 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL13074346 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL6093048 | 0.81 | ERCC1 (0.66) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL18814446 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL6171639 | 0.80 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL2936661 | 0.80 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL2846636 | 0.80 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL28721168 | 0.79 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL20456221 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2APOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700389-A1 | ANTI-ARRHYTHMIC N-SUBSTITUTED 3-BENZAZEPINES OR ISOQUINOLINES | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027971-A1 | ANTI-ARRHYTHMIC N-SUBSTITUTED 3-BENZAZEPINES OR ISOQUINOLINES | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1994-12-08 | — | — | WO | disclosed |