SCHEMBL9028897

SCHEMBL9028897

CCC1=CC=C(CC)CC1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.37
NOS2 P35228 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22642160 0.88 NOS3 (0.37) NOS3NOS2
SCHEMBL2534579 0.86
SCHEMBL19266629 0.86 NOS3 (0.31) NOS3NOS2
SCHEMBL26458737 0.86 NOS3 (0.31) NOS3NOS2
SCHEMBL12345407 0.84
SCHEMBL15037813 0.84
SCHEMBL14234595 0.84
SCHEMBL19141600 0.84
SCHEMBL22019059 0.80
SCHEMBL13289483 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223317-A2 MODULATION OF COMPLEMENT ACTIVITY RA Pharmaceuticals, Inc. (US) 2023-08-09 EP disclosed
EP-2565182-B1 NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE MITSUBISHI TANABE PHARMA CORP (JP) 2017-10-11 EP disclosed
EP-0609289-B1 IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME UPJOHN CO (US) 1996-07-17 EP disclosed
US-5442062-A Treating hypertension, congestive heart failure THE UPJOHN COMPANY (US) 1995-08-15 US disclosed
EP-0609289-A1 IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. UPJOHN CO (US) 1994-08-10 EP disclosed
WO-1994017069-A1 PYRAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF THE UPJOHN COMPANY (US) 1994-08-04 WO disclosed
EP-0540209-A1 Imidazole derivatives and pharmaceutical compositions containing the same THE UPJOHN COMPANY (US) 1993-05-05 EP disclosed
WO-1993008193-A1 IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME THE UPJOHN COMPANY (US) 1993-04-29 WO disclosed