Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903024 | 0.66 | IDO1 (0.33) | IDO1 | |
| SCHEMBL4515365 | 0.65 | IDO1 (0.54) | IDO1 | |
| SCHEMBL4555851 | 0.64 | IDO1 (0.37) | IDO1 | |
| SCHEMBL20582649 | 0.62 | IDO1 (0.35) | IDO1 | |
| SCHEMBL18977949 | 0.58 | IDO1 (0.69) | IDO1 | |
| SCHEMBL17321809 | 0.57 | IDO1 (0.40) | IDO1 | |
| SCHEMBL8690288 | 0.55 | MEN1 (0.59) | IDO1 | |
| SCHEMBL17321751 | 0.55 | IDO1 (0.64) | IDO1 | |
| SCHEMBL17321749 | 0.55 | IDO1 (0.64) | IDO1 | |
| SCHEMBL21316073 | 0.54 | MEN1 (0.63) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708778-A1 | IMIDAZO[1,2-A]PYRAZIN-4-ONE DERIVATIVES FOR USE AS AMPA AND NMDA RECEPTOR ANTAGONISTS | RHONE POULENC RORER SA (FR) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002602-A1 | IMIDAZO(1,2-A)PYRAZIN-4-ONE DERIVATIVES FOR USE AS AMPA AND NMDA RECEPTOR ANTAGONISTS | RHONE-POULENC RORER S.A. (FR) | 1995-01-26 | — | — | WO | disclosed |