SCHEMBL4515365

SCHEMBL4515365

c1ccc2c(c1)N=C1C2=Nc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.54
MAPT P10636 7/20 0.45
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
LMNA P02545 4/20 0.45
ALDH1A1 P00352 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 2/20 0.45
APAF1 O14727 1/20 0.45
HSP90AA1 P07900 1/20 0.45
HSP90AB1 P08238 1/20 0.45
TSHR P16473 1/20 0.45
HK1 P19367 1/20 0.45
GALK1 P51570 1/20 0.45
HKDC1 Q2TB90 1/20 0.45
RECQL P46063 3/20 0.40
SRC P12931 2/20 0.40
CTRB1 P17538 2/20 0.40
CCNE1 P24864 2/20 0.40
CDK2 P24941 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8690288 0.85 MEN1 (0.59) IDO1MAPTMEN1KMT2ALMNA
SCHEMBL18977949 0.84 IDO1 (0.69) IDO1MAPTMEN1KMT2ALMNA
SCHEMBL17321751 0.80 IDO1 (0.64) IDO1MAPTMEN1KMT2ALMNA
SCHEMBL17321749 0.80 IDO1 (0.64) IDO1MAPTMEN1KMT2ALMNA
SCHEMBL21316073 0.78 MEN1 (0.63) IDO1MAPTMEN1KMT2ALMNA
SCHEMBL30816757 0.78 IDO1 (0.69) IDO1MAPTMEN1KMT2ALMNA
SCHEMBL30816758 0.78 IDO1 (0.69) IDO1MAPTMEN1KMT2ALMNA
SCHEMBL12912867 0.77 IDO1 (0.50) IDO1MAPTMEN1KMT2ALMNA
SCHEMBL17321724 0.77 KDM4E (0.52) IDO1MAPTKMT2ALMNAALDH1A1
SCHEMBL13583465 0.77 IDO1 (0.50) IDO1MAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3444257-B1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2021-12-22 EP claimed
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-01-05 US claimed
EP-3444257-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE Boe Technology Group Co. Ltd. (CN) 2019-02-20 EP claimed
US-20180069183-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-03-08 US claimed
US-20230269998-A1 LIGHT EMITTING ELEMENT AND ORGANOMETALLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-24 US disclosed
EP-3444257-B1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2021-12-22 EP disclosed
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-01-05 US disclosed
EP-3444257-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE Boe Technology Group Co. Ltd. (CN) 2019-02-20 EP disclosed
US-20180069183-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-03-08 US disclosed
EP-2618394-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2018-02-21 EP disclosed
EP-2629345-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2017-12-06 EP disclosed
US-9312496-B2 Organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-04-12 US disclosed
EP-1331010-A1 PREVENTIVES AND REMEDIES FOR CENTRAL NERVOUS SYSTEM DISEASES Takeda Chemical Industries, Ltd. (JP) 2003-07-30 EP disclosed
EP-1310490-A1 GPR14 ANTAGONIST Takeda Chemical Industries, Ltd. (JP) 2003-05-14 EP disclosed
EP-1308513-A1 USE OF POLYPEPTIDE Takeda Chemical Industries, Ltd. (JP) 2003-05-07 EP disclosed
US-6534496-B1 Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2003-03-18 US disclosed
US-20020177593-A1 Agents and crystals for improving excretory potency of urinary bladder TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2002-11-28 US disclosed
EP-1118322-A1 DRUGS FOR IMPROVING VESICAL EXCRETORY STRENGTH Takeda Chemical Industries, Ltd. (JP) 2001-07-25 EP disclosed
US-5620973-A CHOLINESTERASE INHIBITOR; ALZHEIMER*S DISEASE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-04-15 US disclosed
EP-0655451-A1 Tetracyclic condensed heterocyclic compounds for the treatment of senile dementia TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230269998-A1 LIGHT EMITTING ELEMENT AND ORGANOMETALLIC COMPOUND FOR THE SAME CRY1, CRY2, NFE2L2 IDO1 902/4885MAPT 995/4885MEN1 340/4885
US-20180069183-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES SLC26A3, SLCO2A1, SLCO2B1 IDO1 3029/4885MAPT 3768/4885MEN1 2443/4885
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices SLC26A3, SLCO2A1, SLCO2B1 IDO1 3029/4885MAPT 3768/4885MEN1 2443/4885
US-20020177593-A1 Agents and crystals for improving excretory potency of urinary bladder ACHE, BPHL, BCHE IDO1 583/4885MAPT 1206/4885MEN1 3760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.