Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029450 | 1.00 | MAOB (0.32) | MAOB | |
| SCHEMBL9028211 | 0.80 | MAOB (0.35) | MAOB | |
| SCHEMBL9028097 | 0.79 | MAOB (0.36) | MAOB | |
| SCHEMBL9027237 | 0.79 | MAOB (0.33) | MAOB | |
| SCHEMBL9028467 | 0.78 | MAOB (0.37) | MAOB | |
| SCHEMBL9028175 | 0.78 | MAOB (0.38) | MAOB | |
| SCHEMBL9029180 | 0.75 | MAOB (0.38) | MAOB | |
| SCHEMBL9028797 | 0.75 | MAOB (0.35) | MAOB | |
| SCHEMBL9028968 | 0.74 | MAOB (0.37) | MAOB | |
| SCHEMBL9028486 | 0.74 | MAOB (0.33) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445827-B1 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO KK (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5149834-A | Anticholesterol agent and enzyme inhibitors, for curing arteriosclerosis | FUJIREBIO INC. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445827-A2 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO INC. (JP) | 1991-09-11 | — | — | EP | disclosed |