Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13813797 | 0.80 | HPGD (0.47) | SLC22A6KDM4EALDH1A1HSD17B10F2 | |
| SCHEMBL27748382 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10F2CYP1A2 | |
| SCHEMBL9029582 | 0.76 | CYP1A2 (0.56) | KDM4EALDH1A1HSD17B10F2CYP1A2 | |
| SCHEMBL2799080 | 0.76 | TNKS2 (0.61) | KDM4EALDH1A1CYP1A2CYP2C19TNKS2 | |
| SCHEMBL31664571 | 0.76 | TNKS2 (0.61) | KDM4EALDH1A1CYP1A2CYP2C19TNKS2 | |
| SCHEMBL9232127 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10F2CYP1A2 | |
| Indoxyl Sulfate SCHEMBL15755 | 0.75 | SLC22A6 (1.00) | SLC22A6ALDH1A1SMN1; SMN2MAPK1CHEK1 | |
| Indoxyl Sulfate SCHEMBL9743592 | 0.75 | SLC22A6 (1.00) | SLC22A6ALDH1A1SMN1; SMN2MAPK1CHEK1 | |
| Indoxyl Sulfate SCHEMBL29377051 | 0.75 | SLC22A6 (1.00) | SLC22A6ALDH1A1SMN1; SMN2MAPK1CHEK1 | |
| SCHEMBL27445663 | 0.74 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10F2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707569-A1 | 4-AMINO-2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-04-24 | — | — | EP | claimed |
| WO-1995000488-A1 | 4-AMINO-2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-01-05 | — | — | WO | claimed |