Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509615 | 0.96 | ESR1 (0.43) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL9608272 | 0.96 | ESR1 (0.43) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL9608266 | 0.96 | ESR1 (0.43) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL8512609 | 0.92 | ESR1 (0.42) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL899859 | 0.89 | ESR2 (0.39) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL899928 | 0.83 | ESR1 (0.38) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL899245 | 0.78 | MEN1 (0.33) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL9608269 | 0.73 | ESR1 (0.41) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL9608276 | 0.71 | MEN1 (0.50) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL8509481 | 0.71 | MEN1 (0.50) | ESR1ESR2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044719-A1 | NORBORNANE-BASED PAC BALLAST AND POSITIVE-TONE PHOTOSENSITIVE RESIN COMPOSITION ENCOMPASSING THE PAC | PROMERUS LLC (US) | 2012-04-05 | — | — | WO | disclosed |