Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030393 | 0.93 | MEN1 (0.38) | CHEK1SHMT2ALOX15TSHRMAPT | |
| SCHEMBL9029741 | 0.89 | KMT2A (0.38) | SHMT2TSHRMAPTCYP3A4MEN1 | |
| SCHEMBL9029914 | 0.88 | HTR2A (0.32) | PPARG | |
| SCHEMBL9031163 | 0.88 | PPARG (0.37) | PPARG | |
| SCHEMBL9030559 | 0.86 | — | — | |
| SCHEMBL9030533 | 0.84 | PPARG (0.33) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9678373 | 0.83 | HTR2A (0.32) | — | |
| SCHEMBL9029661 | 0.83 | KDM4E (0.41) | ALOX15TSHRMAPTTP53CYP3A4 | |
| SCHEMBL9030164 | 0.82 | ALOX5 (0.34) | PPARG | |
| SCHEMBL9029711 | 0.79 | PPARG (0.36) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513285-B1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1996-01-24 | — | — | EP | claimed |
| EP-0513285-B1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1996-01-24 | — | — | EP | disclosed |
| US-5356920-A | Anticholesterol, antilipemic agent | FARMITALIA CARLO ERBA SRL. (IT) | 1994-10-18 | — | — | US | disclosed |