SCHEMBL9030201

SCHEMBL9030201

NCC(Cl)c1csc(Cl)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.32
SLC6A2 P23975 4/20 0.32
SLC6A3 Q01959 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1559961 0.75
Hydrochloric Acid SCHEMBL9031641 0.73 SLC6A2 (0.32) SLC6A2SLC6A3
SCHEMBL12429228 0.69
SCHEMBL23340313 0.68 SLC6A2 (0.35) DAOSLC6A2SLC6A3
SCHEMBL3317983 0.64 TSHR (0.48) SLC6A3
SCHEMBL3695940 0.64 TSHR (0.48) SLC6A3
SCHEMBL3702383 0.64 TSHR (0.48) SLC6A3
SCHEMBL1196519 0.64
SCHEMBL14656821 0.63 SLC6A2 (0.33) SLC6A2SLC6A3
Hydrochloric Acid SCHEMBL355027 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398504-B1 Thieno[3,4-d]azepine derivatives, process for their preparation and pharmaceutical compositions containing them LILLY INDUSTRIES LTD (GB) 1996-06-19 EP disclosed
US-5028602-A Thieno-(3,4-d)azepines, central nervous system disorders LILLY INDUSTRIES LIMITED (GB) 1991-07-02 US disclosed
EP-0398504-A1 Thieno[3,4-d]azepine derivatives, process for their preparation and pharmaceutical compositions containing them LILLY INDUSTRIES LIMITED (GB) 1990-11-22 EP disclosed