Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | PLA2G6 | O60733 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718842 | 0.76 | KDM1A (0.49) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL290575 | 0.76 | TAAR1 (0.42) | KDM1AALDH1A1LMNA | |
| SCHEMBL4723223 | 0.75 | KDM1A (0.47) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL4998332 | 0.73 | HTR2C (0.50) | IDO1ALDH1A1LMNA | |
| SCHEMBL6653603 | 0.72 | GAA (0.45) | SLC6A4SLC6A2SLC6A3ALDH1A1HPGD | |
| SCHEMBL1008916 | 0.70 | KDM1A (0.46) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL497994 | 0.69 | SLC6A4 (0.56) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL3968194 | 0.69 | SLC6A4 (0.56) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL25440356 | 0.68 | KDM1A (0.47) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL11776270 | 0.68 | KDM1A (0.47) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735024-A1 | Antidepressant N-(Heteroarylaminoalkyl)-4-napthyl substituted piperidines and tetrahydroperidines | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5472966-A | Antiserotonin agents; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-05 | — | — | US | disclosed |