Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032752 | 0.96 | MEN1 (0.57) | MEN1KMT2AKCNA5ALDH1A1GFER | |
| SCHEMBL9031331 | 0.92 | KMT2A (0.44) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL9030823 | 0.90 | MEN1 (0.41) | MEN1KMT2AKCNA5ALDH1A1POLB | |
| SCHEMBL9032822 | 0.90 | MEN1 (0.51) | MEN1KMT2APOLBGAATDP1 | |
| SCHEMBL9032560 | 0.88 | MEN1 (0.47) | MEN1KMT2AGAATDP1 | |
| SCHEMBL9032170 | 0.88 | MEN1 (0.46) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL9031546 | 0.85 | MEN1 (0.54) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL9033172 | 0.85 | POLB (0.53) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL9031081 | 0.83 | MEN1 (0.43) | MEN1KMT2APOLBGAATDP1 | |
| SCHEMBL9032250 | 0.83 | KMT2A (0.42) | MEN1KMT2AALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415166-B1 | Process for the preparation of cyanohydantoines | MERCK PATENT GMBH (DE) | 1996-11-20 | — | — | EP | disclosed |
| EP-0415166-A2 | Process for the preparation of cyanohydantoines | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |