Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031331 | 0.89 | KMT2A (0.44) | POLBKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9032822 | 0.87 | MEN1 (0.51) | POLBKMT2ASMN1; SMN2MEN1CYP2C9 | |
| SCHEMBL9030397 | 0.85 | MEN1 (0.54) | POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9032170 | 0.85 | MEN1 (0.46) | POLBKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9032250 | 0.83 | KMT2A (0.42) | POLBKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9032560 | 0.81 | MEN1 (0.47) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9032752 | 0.81 | MEN1 (0.57) | POLBKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL9031081 | 0.79 | MEN1 (0.43) | POLBKMT2ASMN1; SMN2MEN1CYP2C9 | |
| SCHEMBL7692692 | 0.78 | KMT2A (0.48) | POLBKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9032371 | 0.78 | KMT2A (0.48) | POLBKMT2ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415166-B1 | Process for the preparation of cyanohydantoines | MERCK PATENT GMBH (DE) | 1996-11-20 | — | — | EP | disclosed |
| EP-0415166-A2 | Process for the preparation of cyanohydantoines | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |