Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032859 | 0.85 | ADORA1 (0.58) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL8118500 | 0.77 | ADORA1 (0.58) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL8132980 | 0.75 | ADORA1 (0.58) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL6094990 | 0.73 | ADORA1 (0.50) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL6095002 | 0.73 | ADORA1 (0.50) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL9031412 | 0.72 | PDE4A (0.44) | ADORA1ADORA2AADORA2BMEN1LMNA | |
| SCHEMBL8358871 | 0.71 | ADORA3 (0.94) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL5227169 | 0.71 | ADORA1 (0.65) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL8355407 | 0.71 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL8580754 | 0.71 | ADORA3 (0.85) | ADORA3ADORA1ADORA2AADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417790-B1 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5173492-A | Bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0417790-A2 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |