SCHEMBL9030754

SCHEMBL9030754

CC(C)(C)[Si](O[C@H]1C(O)O[C@H](CO)[C@H]1O)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LGALS9 O00182 5/20 0.41
LGALS1 P09382 5/20 0.41
LGALS3 P17931 5/20 0.41
LGALS7; LGALS7B P47929 3/20 0.41
LGALS8 O00214 5/20 0.37
SLC5A2 P31639 4/20 0.35
HK1 P19367 1/20 0.35
HK2 P52789 1/20 0.35
MGAM O43451 1/20 0.34
LGALS2 P05162 1/20 0.34
LGALS4 P56470 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9029247 0.83 SLC5A2 (0.43) SLC5A2
SCHEMBL9029257 0.83 SLC5A2 (0.43) SLC5A2
SCHEMBL10436007 0.83 SLC5A2 (0.43) SLC5A2
SCHEMBL27777436 0.82 SLC5A2 (0.45) SLC5A2
SCHEMBL10767838 0.82 SLC5A2 (0.45) SLC5A2
SCHEMBL27933773 0.82 SLC5A2 (0.45) SLC5A2
SCHEMBL17727876 0.81 SMYD2 (0.34)
SCHEMBL15681534 0.79 SLC5A2 (0.36) LGALS9LGALS1LGALS3LGALS7; LGALS7BSLC5A2
SCHEMBL6559094 0.79 SLC6A2 (0.49) LGALS3LGALS8SLC5A2
SCHEMBL6559086 0.79 SLC6A2 (0.49) LGALS3LGALS8SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0357571-B1 Pyrimidine nucleosides MEDIVIR AB (SE) 1996-04-03 EP disclosed
EP-0691333-A2 Pyrimidine derivatives, process for their preparation and their use as precursors Medivir Aktiebolag (SE) 1996-01-10 EP disclosed
EP-0357571-A2 Pyrimidine nucleosides Medivir Aktiebolag (SE) 1990-03-07 EP disclosed