Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555919 | 0.86 | MRGPRX1 (0.46) | MRGPRX1ST14F2PRSS1PRSS2 | |
| SCHEMBL8995527 | 0.80 | PRSS1 (0.55) | ST14PRSS1PRSS2PRSS3F10 | |
| Hydrochloric Acid SCHEMBL5884387 | 0.79 | PRSS1 (0.53) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9649899 | 0.79 | ESR1 (0.55) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL9650566 | 0.77 | ESR1 (0.58) | SPHK2SPHK1RARB | |
| SCHEMBL9647294 | 0.77 | ESR1 (0.58) | SPHK2SPHK1RARB | |
| SCHEMBL9650482 | 0.77 | ESR1 (0.58) | SPHK2SPHK1RARB | |
| SCHEMBL9650690 | 0.77 | ESR1 (0.58) | SPHK2SPHK1RARB | |
| Hydrochloric Acid SCHEMBL7798271 | 0.77 | SPHK1 (0.56) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL9650583 | 0.77 | ESR1 (0.58) | SPHK2SPHK1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |