Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030810 | 1.00 | PPARG (0.41) | PPARGPPARACRBNSMN1; SMN2MMP1 | |
| SCHEMBL9030719 | 0.89 | PPARG (0.40) | PPARGPPARASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL9030724 | 0.89 | PPARG (0.40) | PPARGPPARASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL9030024 | 0.88 | PPARG (0.41) | PPARGPPARASMN1; SMN2CACNA1BGAA | |
| SCHEMBL9030030 | 0.88 | PPARG (0.41) | PPARGPPARASMN1; SMN2CACNA1BGAA | |
| SCHEMBL9031929 | 0.88 | PPARG (0.40) | PPARGPPARACRBNSMN1; SMN2GAA | |
| SCHEMBL9031920 | 0.88 | PPARG (0.40) | PPARGPPARACRBNSMN1; SMN2GAA | |
| SCHEMBL9031265 | 0.83 | ELANE (0.36) | PPARGPPARASMN1; SMN2CACNA1BALDH1A1 | |
| SCHEMBL9031272 | 0.83 | ELANE (0.36) | PPARGPPARASMN1; SMN2CACNA1BALDH1A1 | |
| SCHEMBL9032528 | 0.73 | FABP7 (0.41) | SMN1; SMN2MMP1MMP9ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558287-B1 | Tetrahydrothiophene derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5292767-A | Tetrahydrothiophene derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0558287-A1 | Tetrahydrothiophene derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |