Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021502 | 0.96 | CHRNA7 (0.57) | CHRNA7HTR3ABCHEACHEGABRP | |
| SCHEMBL9030802 | 0.82 | CHRNA7 (0.58) | CHRNA7HTR3AGABRPGABRDGABRA1 | |
| SCHEMBL5672002 | 0.79 | CHRNA7 (0.54) | CHRNA7HTR3AGABRPGABRDGABRA1 | |
| SCHEMBL5672184 | 0.79 | CHRNA7 (0.54) | CHRNA7HTR3AGABRPGABRDGABRA1 | |
| SCHEMBL8731851 | 0.79 | HTR3A (0.54) | CHRNA7HTR3AGABRPGABRDGABRA1 | |
| SCHEMBL2313692 | 0.78 | ELANE (0.60) | CHRNA7HTR3AGABRPGABRDGABRA1 | |
| SCHEMBL2316032 | 0.78 | ELANE (0.60) | CHRNA7HTR3AGABRPGABRDGABRA1 | |
| SCHEMBL5673336 | 0.77 | ELANE (0.53) | CHRNA7HTR3AALDH1A1L3MBTL1LMNA | |
| SCHEMBL5672094 | 0.77 | ELANE (0.53) | CHRNA7HTR3AALDH1A1L3MBTL1LMNA | |
| SCHEMBL5068679 | 0.77 | CHRNA7 (0.49) | CHRNA7HTR3AGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528734-B1 | Thiazolidin-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-10-23 | — | — | EP | claimed |
| US-5266582-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | claimed |
| EP-0528734-A1 | Thiazolidin-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-24 | — | — | EP | claimed |