Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032855 | 0.94 | AGTR1 (0.45) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| SCHEMBL9030827 | 0.93 | AGTR1 (0.42) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| SCHEMBL9033410 | 0.91 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9262033 | 0.88 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9030832 | 0.88 | AGTR1 (0.42) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| SCHEMBL9031955 | 0.87 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9033635 | 0.87 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9029855 | 0.87 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9031141 | 0.86 | AGTR1 (0.49) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| SCHEMBL27524342 | 0.86 | AGTR1 (0.38) | AGTR1AGTR2ABCB11EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483683-B1 | Thienoimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5463073-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0483683-A2 | Thienoimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-06 | — | — | EP | disclosed |