Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4861904 | 0.67 | P2RX4 (0.34) | GAAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4861911 | 0.67 | P2RX4 (0.34) | GAAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6889091 | 0.66 | RECQL (0.43) | GAAKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL12951634 | 0.65 | CYP2D6 (0.39) | KMT2AMEN1SMN1; SMN2LMNACYP2D6 | |
| SCHEMBL13998263 | 0.65 | CYP2D6 (0.39) | KMT2AMEN1SMN1; SMN2LMNACYP2D6 | |
| SCHEMBL4862023 | 0.65 | CYP2D6 (0.39) | KMT2AMEN1SMN1; SMN2LMNACYP2D6 | |
| SCHEMBL14074341 | 0.65 | CYP2D6 (0.39) | KMT2AMEN1SMN1; SMN2LMNACYP2D6 | |
| SCHEMBL470293 | 0.65 | KDM4E (0.31) | KMT2AMEN1HTTALDH1A1KDM4E | |
| SCHEMBL903069 | 0.63 | GAA (0.33) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL23062876 | 0.62 | BRD4 (0.40) | GAAKMT2AMEN1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044531-A1 | NOVEL PIPERAZINE ANALOGS WITH SUBSTITUTED HETEROARYL GROUPS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |