Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903069 | 0.73 | GAA (0.33) | KDM4EMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL12021938 | 0.67 | SMN1; SMN2 (0.34) | KDM4EMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL903040 | 0.66 | NPC1 (0.30) | HTT | |
| SCHEMBL903098 | 0.65 | GAA (0.36) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL23062876 | 0.63 | BRD4 (0.40) | MEN1ALDH1A1KMT2AHTT | |
| SCHEMBL903082 | 0.63 | ALDH1A1 (0.33) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL903036 | 0.62 | LMNA (0.34) | MEN1KMT2AHTT | |
| SCHEMBL21590983 | 0.62 | LMNA (0.32) | — | |
| SCHEMBL903089 | 0.62 | GAA (0.34) | KDM4EMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL8303828 | 0.60 | ALDH1A1 (0.44) | KDM4EMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033736-A1 | NOVEL PIPERAZINE ANALOGS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-15 | — | — | WO | disclosed |