Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032519 | 1.00 | ACE (0.36) | ACE | |
| SCHEMBL9031875 | 1.00 | ACE (0.36) | ACE | |
| SCHEMBL9032515 | 1.00 | ACE (0.36) | ACE | |
| SCHEMBL9032924 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL9032929 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL9032925 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL9032931 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL11573449 | 0.72 | — | — | |
| SCHEMBL9031557 | 0.71 | — | — | |
| SCHEMBL9031568 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558287-B1 | Tetrahydrothiophene derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5292767-A | Tetrahydrothiophene derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0558287-A1 | Tetrahydrothiophene derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |