Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909347 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A | |
| SCHEMBL6906200 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A | |
| SCHEMBL6907303 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A | |
| SCHEMBL6907299 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A | |
| SCHEMBL9034398 | 0.84 | FPR1 (0.47) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A | |
| SCHEMBL6907434 | 0.84 | FPR1 (0.47) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A | |
| SCHEMBL6903793 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A | |
| SCHEMBL6906802 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A | |
| SCHEMBL6906796 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A | |
| SCHEMBL27514889 | 0.82 | FPR1 (0.45) | SMN1; SMN2L3MBTL1FPR1FPR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706514-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995006034-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1995-03-02 | — | — | WO | disclosed |