Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | CNR2 | P34972 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739008 | 0.79 | MAPT (0.65) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL29506282 | 0.79 | MAPT (0.65) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL8004823 | 0.78 | NPC1 (0.66) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL6686925 | 0.76 | MAPT (0.66) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL29506285 | 0.76 | MAPT (0.66) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL12839874 | 0.74 | CNR2 (0.76) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL1521622 | 0.73 | MAPT (0.58) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL6689412 | 0.73 | MAPT (0.56) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL9436882 | 0.72 | NPC1 (0.72) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL19933073 | 0.72 | CNR2 (0.85) | MAPTNPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041524-A1 | HYDRAZONOPYRAZOLONES AS PROTEIN TYROSINE PHOSPHATASE INHIBITORS | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (MDC) (DE) | 2012-04-05 | — | — | WO | disclosed |