Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695848 | 0.84 | POLB (0.46) | MAPTNPC1RAB9AL3MBTL1GAA | |
| SCHEMBL6688792 | 0.76 | MAPT (0.48) | MAPTNPC1RAB9AL3MBTL1HPGD | |
| SCHEMBL15076954 | 0.74 | MAPT (0.41) | MAPTNPC1RAB9AL3MBTL1GAA | |
| SCHEMBL6689426 | 0.73 | MAPT (0.51) | MAPTNPC1RAB9AL3MBTL1POLB | |
| SCHEMBL14366844 | 0.73 | ALDH1A1 (0.61) | MAPTNPC1RAB9AL3MBTL1GAA | |
| SCHEMBL6687325 | 0.73 | CNR2 (0.46) | MAPTNPC1RAB9AL3MBTL1HPGD | |
| SCHEMBL903237 | 0.73 | MAPT (0.65) | MAPTNPC1RAB9AL3MBTL1GAA | |
| SCHEMBL6687343 | 0.72 | MAPT (1.00) | MAPTNPC1RAB9AL3MBTL1GAA | |
| SCHEMBL6694633 | 0.72 | LMNA (0.41) | MAPTNPC1RAB9APOLBALOX15 | |
| SCHEMBL6694669 | 0.70 | MAPK1 (0.43) | MAPTNPC1RAB9AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |